Research Methods and Approaches

As clinicians’ options for treatment, diagnosis, and prevention of health conditions increase, research to evaluate the effectiveness of these methods becomes more important. With so many options and new interventions being developed, pediatrician research is challenged with accelerating the process for determining which treatments work best, both in terms of benefits to patients and potential adverse effects.

CPCE conducts research that leads to informed and effective decision-making. CPCE investigators are experts in the methods of clinical epidemiology and health services research. Our experts apply the appropriate state-of-the-science research methods to answer specific clinical questions.

In an era of Big Data, many CPCE studies take advantage of existing databases of health information that encompass broad population groups allowing for timely and efficient analyses. As part of its commitment to translational research excellence, The Children’s Hospital of Philadelphia Research Institute has dedicated resources focusing on using technologies, such as its integrated electronic medical records, to improve the outcomes of pediatric patients around the world. CPCE researchers use approaches designed to test the effectiveness of medical interventions, health care practices (such as stewardship programs or clinical pathways), and systems, as well as to design and test implementation strategies.

Methods and Approaches for Pediatric Research

CPCE investigators employ various approaches, research designs, statistical tools and analytic models to conduct clinical effectiveness research both prospectively and retrospectively. Read more: