Peer-Reviewed Publications

CPCE investigators are international experts in their clinical effectiveness-related fields, and have authored hundreds of pediatric research articles in leading peer-reviewed journals. From here you can access CPCE journal article abstracts by author, title, or year.

Found 19 results
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Downes KJ, Goldstein SL, Vinks AA. "Increased Vancomycin Exposure and Nephrotoxicity in Children: Therapeutic Does Not Mean Safe." J Pediatric Infect Dis Soc. 2016;5(1):65-7.
Downes KJ, Weiss SL, Gerber JS, et al. "A Pragmatic Biomarker-Driven Algorithm to Guide Antibiotic Use in the Pediatric Intensive Care Unit: The Optimizing Antibiotic Strategies in Sepsis (OASIS) Study." J Pediatric Infect Dis Soc. 2016.
Downes KJ, Rao MB, Kahill L, Nguyen H, Clancy JP, Goldstein SL. "Daily serum creatinine monitoring promotes earlier detection of acute kidney injury in children and adolescents with cystic fibrosis." J. Cyst. Fibros.. 2014;13(4):435-41.
Downes KJ, Patil NR, Rao MB, et al. "Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis." Pediatr. Nephrol.. 2015;30(10):1879-88.
Downes KJ, Dong M, Fukuda T, et al. "Urinary kidney injury biomarkers and tobramycin clearance among children and young adults with cystic fibrosis: a population pharmacokinetic analysis." J. Antimicrob. Chemother.. 2017;72(1):254-60.
Downes KJ, Cowden C, Laskin BL, et al. "Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children." JAMA Pediatr. 2017:e173219.
Downes KJ, Laskin BL, Fisher BT. "The Cost of Vancomycin and Piperacillin/Tazobactam Treatment-Reply." JAMA Pediatr. 2018.
Downes KJ. "Continuous-Infusion Vancomycin-Teaching an Old Dog New Tricks?" J Pediatric Infect Dis Soc. 2018.
Downes KJ, Ellis D, Lavigne S, Bryan M, Zaoutis TE, Fisher BT. "The use of echinocandins in hospitalized children in the United States." Med. Mycol.. 2018.
Downes KJ, Fitzgerald JC, Schriver E, et al. "Implementation of a Pragmatic Biomarker-Driven Algorithm to Guide Antibiotic Use in the Pediatric Intensive Care Unit: the Optimizing Antibiotic Strategies in Sepsis (OASIS) II Study." J Pediatric Infect Dis Soc. 2018.
Downes KJ, Hayes M, Fitzgerald JC, et al. "Mechanisms of antimicrobial-induced nephrotoxicity in children." J. Antimicrob. Chemother.. 2019.
Downes KJ, Fisher BT, Zane NR. "Administration and Dosing of Systemic Antifungal Agents in Pediatric Patients." Paediatr Drugs. 2020.
Downes KJ, Boge CLK, Baro E, et al. "Acute Kidney Injury During Treatment with Intravenous Acyclovir for Suspected or Confirmed Neonatal Herpes Simplex Virus Infection." J. Pediatr.. 2020.
Downes KJ, Fitzgerald JC, Weiss SL. "Utility of Procalcitonin as a Biomarker for Sepsis in Children." J. Clin. Microbiol.. 2020.
Downes KJ, Danziger-Isakov LA, Cousino MK, et al. "Return to School for Pediatric Solid Organ Transplant Recipients in the United States During the COVID-19 Pandemic: Expert Opinion on Key Considerations and Best Practices." J Pediatric Infect Dis Soc. 2020.
Downes KJ, Zane NR, Zuppa AF. "Effect of Cystatin C on Vancomycin Clearance Estimation in Critically Ill Children Using a Population Pharmacokinetic Modeling Approach." Ther Drug Monit. 2020.
Downes KJ, Goldman JL. "Too much of a good thing: defining antimicrobial therapeutic targets to minimize toxicity." Clin Pharmacol Ther. 2021.
Downes KJ. "Procalcitonin in Pediatric Sepsis: What Is It Good for?" J Pediatric Infect Dis Soc. 2021.
Downes KJ, Statler VA, Orscheln RC, et al. "Return to School and COVID-19 Vaccination for Pediatric Solid Organ Transplant Recipients in the United States: Expert Opinion for 2021-2022." J Pediatric Infect Dis Soc. 2021.