Peer-Reviewed Publications

CPCE investigators are international experts in their clinical effectiveness-related fields, and have authored hundreds of pediatric research articles in leading peer-reviewed journals. From here you can access CPCE journal article abstracts by author, title, or year.

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Downes KJ. "Procalcitonin in Pediatric Sepsis: What Is It Good for?" J Pediatric Infect Dis Soc. 2021.
Downes KJ, Patil NR, Rao MB, et al. "Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis." Pediatr. Nephrol.. 2015;30(10):1879-88.
Downes KJ, Laskin BL, Fisher BT. "The Cost of Vancomycin and Piperacillin/Tazobactam Treatment-Reply." JAMA Pediatr. 2018.
Downes KJ, Zane NR, Zuppa AF. "Effect of Cystatin C on Vancomycin Clearance Estimation in Critically Ill Children Using a Population Pharmacokinetic Modeling Approach." Ther Drug Monit. 2020.
Downes KJ, Fisher BT, Zane NR. "Administration and Dosing of Systemic Antifungal Agents in Pediatric Patients." Paediatr Drugs. 2020.
Downes KJ, Fitzgerald JC, Schriver E, et al. "Implementation of a Pragmatic Biomarker-Driven Algorithm to Guide Antibiotic Use in the Pediatric Intensive Care Unit: the Optimizing Antibiotic Strategies in Sepsis (OASIS) II Study." J Pediatric Infect Dis Soc. 2018.
Downes KJ, Rao MB, Kahill L, Nguyen H, Clancy JP, Goldstein SL. "Daily serum creatinine monitoring promotes earlier detection of acute kidney injury in children and adolescents with cystic fibrosis." J. Cyst. Fibros.. 2014;13(4):435-41.
Downes KJ, Statler VA, Orscheln RC, et al. "Return to School and COVID-19 Vaccination for Pediatric Solid Organ Transplant Recipients in the United States: Expert Opinion for 2021-2022." J Pediatric Infect Dis Soc. 2021.
Downes KJ, Boge CLK, Baro E, et al. "Acute Kidney Injury During Treatment with Intravenous Acyclovir for Suspected or Confirmed Neonatal Herpes Simplex Virus Infection." J. Pediatr.. 2020.
Downes KJames, Barreto EFrazee. "Estimating renal function for drug dosing in critically ill patients with persistent inflammation, immunosuppression and catabolism syndrome." Intern Emerg Med. 2021.
Downes KJ, Goldstein SL, Vinks AA. "Increased Vancomycin Exposure and Nephrotoxicity in Children: Therapeutic Does Not Mean Safe." J Pediatric Infect Dis Soc. 2016;5(1):65-7.
Downes KJ, Cowden C, Laskin BL, et al. "Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children." JAMA Pediatr. 2017:e173219.
Downes KJ, Ellis D, Lavigne S, Bryan M, Zaoutis TE, Fisher BT. "The use of echinocandins in hospitalized children in the United States." Med. Mycol.. 2018.
Downes KJ, Fitzgerald JC, Weiss SL. "Utility of Procalcitonin as a Biomarker for Sepsis in Children." J. Clin. Microbiol.. 2020.
Downes KJ. "Continuous-Infusion Vancomycin-Teaching an Old Dog New Tricks?" J Pediatric Infect Dis Soc. 2018.
Downes KJ, Goldman JL. "Too much of a good thing: defining antimicrobial therapeutic targets to minimize toxicity." Clin Pharmacol Ther. 2021.
Downes KJ, Danziger-Isakov LA, Cousino MK, et al. "Return to School for Pediatric Solid Organ Transplant Recipients in the United States During the COVID-19 Pandemic: Expert Opinion on Key Considerations and Best Practices." J Pediatric Infect Dis Soc. 2020.
Doupnik SK, Lawlor J, Zima BT, et al. "Mental Health Conditions and Unplanned Hospital Readmissions in Children." J Hosp Med. 2018;13(7):445-452.
Doupnik SK, Rodean J, Feinstein J, et al. "Healthcare Utilization and Spending for Children with Mental Health Conditions in Medicaid." Acad Pediatr. 2020.
Doupnik SK, Lawlor J, Zima BT, et al. "Mental Health Conditions and Medical and Surgical Hospital Utilization." Pediatrics. 2016;138(6).
Doupnik S, Rodean J, Zima BT, et al. "Readmissions after Pediatric Hospitalization for Suicide Ideation and Suicide Attempt." J Hosp Med. 2018;13(11):743-751.
Doupnik SK, Dunn M. "A Novel Pathway for Somatic Symptoms: Strategies for Successful Pathway Implementation." Hosp Pediatr. 2019.
Doupnik SK, Esposito J, Lavelle J. "Beyond Mental Health Crisis Stabilization in Emergency Departments and Acute Care Hospitals." Pediatrics. 2018;141(5).
Doupnik SK, Feudtner C, Marcus SC. "Family Report Compared to Clinician-Documented Diagnoses for Psychiatric Conditions Among Hospitalized Children." J Hosp Med. 2017;12.
Doupnik SK, Walter JK. "Collaboration Is Key to Improving Hospital Care for Patients With Medical and Psychiatric Comorbidity." Hosp Pediatr. 2016.