Use of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study.

TitleUse of Concomitant Antibiotics During Treatment for Clostridium difficile Infection (CDI) in Pediatric Inpatients: An Observational Cohort Study.
Publication TypeJournal Article
Year of Publication2016
AuthorsStevens VW, Thurm C, Schwab EM, Kronman MP, Gerber JS, Shah SS, Newland JG, Courter J, Parker S, Brogan TV, Hersh AL
JournalInfect Dis Ther
Volume5
Issue1
Pagination45-51
Date Published2016 Mar
ISSN2193-8229
Abstract

Concomitant antibiotic use during treatment for Clostridium difficile infection (CDI) increases the risk of recurrence. Across a network of children's hospitals, 46% of patients treated for CDI received concomitant antibiotics for a median of 7 days. Concomitant antibiotic use was more common among patients with malignancies, and solid organ or bone marrow transplant. Unnecessary concomitant antibiotic use in CDI patients is a potential target for pediatric antimicrobial stewardship.

DOI10.1007/s40121-016-0105-2
Alternate JournalInfect Dis Ther
PubMed ID26972929