Tuberculosis in Adolescents and Young Adults: Emerging Data on TB Transmission and Prevention among Vulnerable Young People.

TitleTuberculosis in Adolescents and Young Adults: Emerging Data on TB Transmission and Prevention among Vulnerable Young People.
Publication TypeJournal Article
Year of Publication2021
AuthorsLaycock KM, Enane LA, Steenhoff AP
JournalTrop Med Infect Dis
Volume6
Issue3
Date Published2021 Aug 05
ISSN2414-6366
Abstract

Adolescents and young adults (AYA, ages 10-24 years) comprise a uniquely important but understudied population in global efforts to end tuberculosis (TB), the leading infectious cause of death by a single agent worldwide prior to the COVID-19 pandemic. While TB prevention and care strategies often overlook AYA by grouping them with either children or adults, AYA have particular physiologic, developmental, and social characteristics that require dedicated approaches. This review describes current evidence on the prevention and control of TB among AYA, including approaches to TB screening, dynamics of TB transmission among AYA, and management challenges within the context of unique developmental needs. Challenges are considered for vulnerable groups of AYA such as migrants and refugees; AYA experiencing homelessness, incarceration, or substance use; and AYA living with HIV. We outline areas for needed research and implementation strategies to address TB among AYA globally.

DOI10.3390/tropicalmed6030148
Alternate JournalTrop Med Infect Dis
PubMed ID34449722
Grant ListK23 HD095778 / NH / NIH HHS / United States
P30 AI 045008 / NH / NIH HHS / United States