Trends in Intravenous Magnesium Use and Outcomes for Status Asthmaticus in Children's Hospitals from 2010 to 2017.

TitleTrends in Intravenous Magnesium Use and Outcomes for Status Asthmaticus in Children's Hospitals from 2010 to 2017.
Publication TypeJournal Article
Year of Publication2020
AuthorsMittal V, Hall M, Antoon J, Gold J, Kenyon C, Parikh K, Morse R, Quinonez R, Teufel RJ, Shah SS
JournalJ Hosp Med
Volume15
Issue7
Pagination403-406
Date Published2020 07 01
ISSN1553-5606
KeywordsAdministration, Intravenous, Adolescent, Child, Child, Preschool, Female, Hospitalization, Hospitals, Pediatric, Humans, Intensive Care Units, Pediatric, Length of Stay, Magnesium, Male, Retrospective Studies, Status Asthmaticus
Abstract

Intravenous (IV) magnesium is used as an adjunct therapy in management of status asthmaticus with a goal of reducing intubation rate. A recent review suggests that IV magnesium use in status asthmaticus reduces admission rates. This is contrary to the observation of practicing emergency room physicians. The goal of this study was to assess trends in IV magnesium use for status asthmaticus in US children's hospitals over 8 years through a retrospective analysis of children younger than 18 years using the Pediatric Health Information System database. Outcomes were IV magnesium use, inpatient and intensive care unit admission rate, geometric mean length of stay, and 7-day all-cause readmission rate. IV magnesium use for asthma hospitalization more than doubled over 8 years (17% vs. 36%; P < .001). Yearly trends were not significantly associated with hospital or intensive care unit admission rate or 7-day all-cause readmissions, although length of stay was reduced (P < .001).

DOI10.12788/jhm.3405
Alternate JournalJ Hosp Med
PubMed ID32584247
PubMed Central IDPMC7402601
Grant ListK12 HL137943 / HL / NHLBI NIH HHS / United States