Title | Successful treatment of pulmonary mucormycosis in two pediatric hematopoietic stem cell transplant patients. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Elgarten CW, Levy EM, Mattei P, Fisher BT, Olson TS, Freedman JL |
Journal | Pediatr Transplant |
Volume | 22 |
Start Page | e13270 |
Issue | 7 |
Pagination | e13270 |
Date Published | 2018 Nov |
ISSN | 1399-3046 |
Abstract | Pulmonary mucormycosis diagnosed immediately after hematopoietic stem cell transplantation frequently portends a poor prognosis. However, here we describe two cases in children that were treated successfully to highlight the efficacy of a multidisciplinary approach. Despite diagnosis in the immediate post-transplant period and requirement for ongoing immunosuppression to prevent or treat GVHD, both are long-term survivors due to early surgical debridement with transfusion support and prompt initiation of targeted antifungal therapy. In the absence of evidence-based treatment guidelines, survival of pulmonary mucormycosis is achievable even in high-risk patients with a multidisciplinary team to guide management. |
DOI | 10.1111/petr.13270 |
Alternate Journal | Pediatr Transplant |
PubMed ID | 30014584 |