Risk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients.

TitleRisk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients.
Publication TypeJournal Article
Year of Publication2012
AuthorsHan JH, Nachamkin I, Zaoutis TE, Coffin SE, Linkin DR, Fishman NO, Weiner MG, Hu B, Tolomeo P, Lautenbach E
JournalInfect Control Hosp Epidemiol
Volume33
Issue12
Pagination1242-5
Date Published2012 Dec
ISSN1559-6834
KeywordsAdult, Aged, Anti-Bacterial Agents, beta-Lactam Resistance, beta-Lactamases, Carrier State, Case-Control Studies, Clindamycin, Escherichia coli, Female, Gastrointestinal Tract, Humans, Klebsiella, Length of Stay, Liver Cirrhosis, Male, Microbial Sensitivity Tests, Middle Aged, Prevalence, Rectum, Risk Factors, Thienamycins
Abstract

We describe the prevalence of and risk factors for colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species (ESBL-EK) in hospitalized patients. The prevalence of colonization with ESBL-EK was 2.6%. Colonization was associated with cirrhosis, longer duration of hospital stay prior to surveillance, and prior exposure to clindamycin or meropenem.

DOI10.1086/668443
Alternate JournalInfect Control Hosp Epidemiol
PubMed ID23143363
PubMed Central IDPMC3983276
Grant ListK24 AI080942 / AI / NIAID NIH HHS / United States
K24 AI080942 / AI / NIAID NIH HHS / United States
R01-CI000389 / CI / NCPDCID CDC HHS / United States
U54-CK000163 / CK / NCEZID CDC HHS / United States