Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn?

TitlePrevention of bacterial infection in pediatric oncology: what do we know, what can we learn?
Publication TypeJournal Article
Year of Publication2012
AuthorsAlexander S, Nieder M, Zerr DM, Fisher BT, Dvorak CC, Sung L
JournalPediatr Blood Cancer
Volume59
Issue1
Pagination16-20
Date Published2012 Jul 15
ISSN1545-5017
KeywordsAdolescent, Bacterial Infections, Child, Child, Preschool, Female, Humans, Infant, Infection Control, Male, Neoplasms, Risk Factors, Sepsis
Abstract

Bacterial sepsis continues to be a leading cause of morbidity and toxic death in children receiving intensive therapy for cancer. Empiric therapy for suspected infections and treatment of documented infections are well-established standards of care. The routine use of prophylactic strategies is much less common in pediatric oncology. This paper will review the current literature on the use and risks of antimicrobial prophylaxis as well as non-pharmacological methods for infection prevention and will address areas in need of further research.

DOI10.1002/pbc.23416
Alternate JournalPediatr Blood Cancer
PubMed ID22102612
PubMed Central IDPMC4008322
Grant ListU10 CA095861 / CA / NCI NIH HHS / United States
U10 CA098543 / CA / NCI NIH HHS / United States
U10 CA98543-08 / CA / NCI NIH HHS / United States
/ / Canadian Institutes of Health Research / Canada