Prevalence and characteristics of antimicrobial stewardship programs at freestanding children's hospitals in the United States.

TitlePrevalence and characteristics of antimicrobial stewardship programs at freestanding children's hospitals in the United States.
Publication TypeJournal Article
Year of Publication2014
AuthorsNewland JG, Gerber JS, Weissman SJ, Shah SS, Turgeon C, Hedican EB, Thurm C, Hall M, Courter J, Brogan TV, Maples H, Lee BR, Hersh AL
JournalInfect Control Hosp Epidemiol
Volume35
Issue3
Pagination265-71
Date Published2014 Mar
ISSN1559-6834
KeywordsAnti-Bacterial Agents, Child, Data Collection, Drug Utilization Review, Feedback, Hospitals, Pediatric, Humans, Prevalence, United States
Abstract

BACKGROUND AND OBJECTIVE: Antimicrobial stewardship programs (ASPs) are a mechanism to ensure the appropriate use of antimicrobials. The extent to which ASPs are formally implemented in freestanding children's hospitals is unknown. The objective of this study was to determine the prevalence and characteristics of ASPs in freestanding children's hospitals.

METHODS: We conducted an electronic survey of 42 freestanding children's hospitals that are members of the Children's Hospital Association to determine the presence and characteristics of their ASPs. For hospitals without an ASP, we determined whether stewardship strategies were in place and whether there were barriers to implementing a formal ASP.

RESULTS: We received responses from 38 (91%) of 42. Among responding institutions, 16 (38%) had a formal ASP, and 15 (36%) were in the process of implementing a program. Most ASPs (13 [81%] of 16) were started after 2007. The median number of full-time equivalents dedicated to ASPs was 0.63 (range, 0.1-1.8). The most common antimicrobials monitored by ASPs were linezolid, vancomycin, and carbapenems. Many hospitals without a formal ASP were performing stewardship activities, including elements of prospective audit and feedback (9 [41%] of 22), formulary restriction (9 [41%] of 22), and use of clinical guidelines (17 [77%] of 22). Antimicrobial outcomes were more likely to be monitored by hospitals with ASPs (100% vs 68%; P = .01), although only 1 program provided support for a data analyst.

CONCLUSIONS: Most freestanding children's hospitals have implemented or are developing an ASP. These programs differ in structure and function, and more data are needed to identify program characteristics that have the greatest impact.

DOI10.1086/675277
Alternate JournalInfect Control Hosp Epidemiol
PubMed ID24521592
Grant ListU18-HS10399 / HS / AHRQ HHS / United States