Positive Two-tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the U.S.

TitlePositive Two-tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the U.S.
Publication TypeJournal Article
Year of Publication2018
AuthorsGarro A, Bennett J, Balamuth F, Levas MN, Neville D, Branda JC, Maulden AB, Lantos PM, Nigrovic LE
Corporate AuthorsPedi Lyme Net
JournalPediatr Infect Dis J
Date Published2018 Jul 31
ISSN1532-0987
Abstract

Knowing the frequency of positive Lyme disease serology in children without signs of infection facilitates test interpretation. Of 315 asymptomatic children from Lyme disease endemic regions, 32 had positive or equivocal C6 enzyme linked immunoassays, but only 5 had positive IgG or IgM supplemental immunoblots (1.6%, 95% confidence interval 0.7-3.7%).

DOI10.1097/INF.0000000000002157
Alternate JournalPediatr. Infect. Dis. J.
PubMed ID30067595