Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals.

TitlePerinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals.
Publication TypeJournal Article
Year of Publication2022
AuthorsFlannery DD, Barboza AZevallos, Pfeifer MR, Hudak ML, Barnette K, Getzlaff TR, Ellington SR, Woodworth KR, Dhudasia MB, Mukhopadhyay S, Weinberg DD, Foglia EE, Puopolo KM
JournalJ Perinatol
Date Published2022 Jul 01
ISSN1476-5543
Abstract

OBJECTIVE: Describe 1-month outcomes among newborns of persons with perinatal COVID-19.

STUDY DESIGN: Prospective observational study of pregnant persons who tested positive for SARS-CoV-2 between 14 days before and 3 days after delivery and their newborns, from 3/2020 to 3/2021 at two urban high-risk academic hospitals. Phone interviews were conducted to determine 1-month newborn outcomes.

RESULTS: Among 9748 pregnant persons, 209 (2.1%) tested positive for perinatal SARS-CoV-2. Symptomatically infected persons were more likely to have a preterm delivery due to worsening maternal condition and their newborns were more likely to test positive for SARS-CoV-2 compared with asymptomatic persons. Six of 191 (3.1%) infants tested were positive for SARS-CoV-2; none had attributable illness before discharge. Of 169 eligible families, 132 (78.1%) participated in post-discharge interviews; none reported their newborn tested positive for SARS-CoV-2 by 1 month of age.

CONCLUSION: Symptomatic perinatal COVID-19 had a substantial effect on maternal health but no apparent short-term effect on newborns.

DOI10.1038/s41372-022-01446-x
Alternate JournalJ Perinatol
PubMed ID35778485