Noninvasive Respiratory Support.

TitleNoninvasive Respiratory Support.
Publication TypeJournal Article
Year of Publication2016
AuthorsCummings JJ, Polin RA
Corporate AuthorsCommittee on Fetus and Newborn, American Academy of Pediatrics
JournalPediatrics
Volume137
Issue1
Date Published2016 Jan
ISSN1098-4275
KeywordsHumans, Infant, Premature, Noninvasive Ventilation, Respiratory Insufficiency
Abstract

Mechanical ventilation is associated with increased survival of preterm infants but is also associated with an increased incidence of chronic lung disease (bronchopulmonary dysplasia) in survivors. Nasal continuous positive airway pressure (nCPAP) is a form of noninvasive ventilation that reduces the need for mechanical ventilation and decreases the combined outcome of death or bronchopulmonary dysplasia. Other modes of noninvasive ventilation, including nasal intermittent positive pressure ventilation, biphasic positive airway pressure, and high-flow nasal cannula, have recently been introduced into the NICU setting as potential alternatives to mechanical ventilation or nCPAP. Randomized controlled trials suggest that these newer modalities may be effective alternatives to nCPAP and may offer some advantages over nCPAP, but efficacy and safety data are limited.

DOI10.1542/peds.2015-3758
Alternate JournalPediatrics
PubMed ID26715607