Musculoskeletal complications following total body irradiation in hematopoietic stem cell transplant patients.

TitleMusculoskeletal complications following total body irradiation in hematopoietic stem cell transplant patients.
Publication TypeJournal Article
Year of Publication2018
AuthorsJackson TJ, Mostoufi-Moab S, Hill-Kayser C, Balamuth NJ, Arkader A
JournalPediatr Blood Cancer
Volume65
Issue4
Date Published2018 Apr
ISSN1545-5017
Abstract

Total body irradiation (TBI) is commonly used in conditioning regimens for allogeneic hematopoietic stem cell transplantation (HSCT) to treat benign and malignant disease. Though life-saving, these therapies place patients at risk for important side effects, including musculoskeletal complications such as short stature, osteonecrosis, slipped capital femoral epiphysis, and the development of benign and malignant bone tumors. With an increasing number of HSCT survivors, there is a growing need for awareness of the musculoskeletal complications of HSCT and TBI.

DOI10.1002/pbc.26905
Alternate JournalPediatr Blood Cancer
PubMed ID29286549