Management of pediatric differentiated thyroid cancer: An overview for the pediatric oncologist.

TitleManagement of pediatric differentiated thyroid cancer: An overview for the pediatric oncologist.
Publication TypeJournal Article
Year of Publication2020
AuthorsPrasad PK, Mahajan P, Hawkins DS, Mostoufi-Moab S, Venkatramani R
JournalPediatr Blood Cancer
Paginatione28141
Date Published2020 Apr 10
ISSN1545-5017
Abstract

Differentiated thyroid cancer (DTC) is the most common childhood thyroid malignancy. The standard of care for pediatric DTC is total thyroidectomy followed by radioactive iodine (RAI) treatment when indicated. Molecular changes and potential therapeutic targets have been recently described in pediatric thyroid cancer. Pediatric oncologists are increasingly involved in the evaluation of thyroid nodules in childhood cancer survivors and in the management of advanced thyroid cancer. In 2015, the American Thyroid Association published management guidelines for children with DTC. We provide an overview of the current standard of care and highlight available targeted therapies for progressive or RAI refractory DTC.

DOI10.1002/pbc.28141
Alternate JournalPediatr Blood Cancer
PubMed ID32275118