Fluoroquinolone resistance in pediatric bloodstream infections because of Escherichia coli and Klebsiella species.

TitleFluoroquinolone resistance in pediatric bloodstream infections because of Escherichia coli and Klebsiella species.
Publication TypeJournal Article
Year of Publication2008
AuthorsKim JY, Lautenbach E, Chu J, Goyal M, Nachamkin I, McGowan KL, Coffin SE, Zaoutis TE
JournalAm J Infect Control
Volume36
Issue1
Pagination70-3
Date Published2008 Feb
ISSN1527-3296
KeywordsAdolescent, Anti-Bacterial Agents, Bacteremia, beta-Lactamases, Case-Control Studies, Child, Drug Resistance, Bacterial, Escherichia coli, Female, Fluoroquinolones, Humans, Klebsiella, Male, Risk Factors
Abstract

In pediatric bloodstream infections with fluoroquinolone (FQ)-resistant Escherichia coli and Klebsielia species, we noted an association between FQ resistance and extended-spectrum beta-lactamase (ESBL) production (OR, 12; 95% CI: 2.28-83.8). A case control study revealed no significant risk factors (including prior antibiotic use) for FQ resistance among ESBL E coli and Klebsiella species (ESBL-EK).

DOI10.1016/j.ajic.2007.01.012
Alternate JournalAm J Infect Control
PubMed ID18241740
Grant ListU18-HS10399 / HS / AHRQ HHS / United States