Feasibility and preliminary effectiveness of a novel mobility training intervention in infants and toddlers with cerebral palsy.

TitleFeasibility and preliminary effectiveness of a novel mobility training intervention in infants and toddlers with cerebral palsy.
Publication TypeJournal Article
Year of Publication2012
AuthorsProsser LA, Ohlrich LB, Curatalo LA, Alter KE, Damiano DL
JournalDev Neurorehabil
Volume15
Issue4
Pagination259-66
Date Published2012
ISSN1751-8431
KeywordsCerebral Palsy, Child Development, Child, Preschool, Feasibility Studies, Female, Humans, Infant, Male, Motor Skills, Pilot Projects, Treatment Outcome
Abstract

OBJECTIVE: To design a novel mobility training intervention incorporating infant motor learning and neurorehabilitation principles and investigate its feasibility, tolerability and effect on motor development in toddlers with cerebral palsy (CP).

METHODS: A single-subject research design with repeated measures during 6-week baseline and intervention phases and after treatment withdrawal was used. Five participants attended therapy utilizing novel dynamic weight assistance technology, which allowed practice of motor skills beyond participants' current abilities.

RESULTS: Average attendance and engagement rates exceeded 90%. Gains in gross motor function were observed after treatment that exceeded the expected rate in four of the five participants. Rates of motor development during treatment were 10.8, 3.8, 7.0, 15.1, and 0.3 times greater than during baseline for the five participants, respectively.

CONCLUSIONS: This intervention was tolerated and demonstrated the potential to alter the trajectory of motor development in CP, providing proof of concept for further investigation.

DOI10.3109/17518423.2012.687782
Alternate JournalDev Neurorehabil
PubMed ID22670679
PubMed Central IDPMC3594802
Grant ListZ99 CL999999 / / Intramural NIH HHS / United States