Factors associated with self-reported adherence among adolescents on antiretroviral therapy in Zimbabwe.

TitleFactors associated with self-reported adherence among adolescents on antiretroviral therapy in Zimbabwe.
Publication TypeJournal Article
Year of Publication2015
AuthorsGross R, Bandason T, Langhaug L, Mujuru H, Lowenthal ED, Ferrand R
JournalAIDS Care
Volume27
Issue3
Pagination322-6
Date Published2015
ISSN1360-0451
KeywordsAdolescent, Adult, Anti-HIV Agents, Child, Counseling, Cross-Sectional Studies, Female, HIV Infections, Humans, Male, Medication Adherence, Risk Factors, Self Report, Zimbabwe
Abstract

Nonadherence to medication is the key obstacle to human immunodeficiency virus (HIV) treatment success. The group at highest risk of nonadherence is adolescents, but relatively little is known about risk factors for and protective factors against poor adherence in this age group. We undertook a cross-sectional study of 262 HIV-infected adolescents aged 10-19 years on antiretroviral therapy at two clinics in Harare, Zimbabwe, to investigate personal and system-level factors associated with optimal self-reported adherence. Suboptimal adherence was common with only 101 (39%) reporting "excellent" adherence. Having the guardian present at each clinical encounter, comfort with asking questions to the health provider and participating in group sessions led by a professional facilitator were all significantly associated with excellent adherence (p < 0.05). Strengthening the parent-child dyad and professional-led groups as strategies to improve adherence should be evaluated.

DOI10.1080/09540121.2014.969676
Alternate JournalAIDS Care
PubMed ID25338010
PubMed Central IDPMC4305494
Grant ListK23 MH095669 / MH / NIMH NIH HHS / United States
K23 MH095669 / MH / NIMH NIH HHS / United States
P30 AI 045008 / AI / NIAID NIH HHS / United States
P30 AI045008 / AI / NIAID NIH HHS / United States