Epidemiology and diagnosis of health care-associated infections in the NICU.

TitleEpidemiology and diagnosis of health care-associated infections in the NICU.
Publication TypeJournal Article
Year of Publication2012
AuthorsPolin RA, Denson S, Brady MT
Corporate AuthorsCommittee on fetus and newborn, Committee on Infectious Diseases
JournalPediatrics
Volume129
Issue4
Paginatione1104-9
Date Published2012 Apr
ISSN1098-4275
KeywordsCross Infection, Global Health, Humans, Incidence, Infant, Newborn, Infectious Disease Transmission, Professional-to-Patient, Intensive Care Units, Neonatal
Abstract

Health care-associated infections in the NICU are a major clinical problem resulting in increased morbidity and mortality, prolonged length of hospital stays, and increased medical costs. Neonates are at high risk for health care-associated infections because of impaired host defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of neonatal skin, the use of invasive procedures and devices, and frequent exposure to broad-spectrum antibiotics. This statement will review the epidemiology and diagnosis of health care-associated infections in newborn infants.

DOI10.1542/peds.2012-0147
Alternate JournalPediatrics
PubMed ID22451708