Elimination of Perinatal Hepatitis B: Providing the First Vaccine Dose Within 24 Hours of Birth.

TitleElimination of Perinatal Hepatitis B: Providing the First Vaccine Dose Within 24 Hours of Birth.
Publication TypeJournal Article
Year of Publication2017
Corporate AuthorsCommittee on Infectious Diseases, Committee on fetus and newborn
JournalPediatrics
Volume140
Issue3
Date Published2017 Sep
ISSN1098-4275
Abstract

After the introduction of the hepatitis B vaccine in the United States in 1982, a greater than 90% reduction in new infections was achieved. However, approximately 1000 new cases of perinatal hepatitis B infection are still identified annually in the United States. Prevention of perinatal hepatitis B relies on the proper and timely identification of infants born to mothers who are hepatitis B surface antigen positive and to mothers with unknown status to ensure administration of appropriate postexposure immunoprophylaxis with hepatitis B vaccine and immune globulin. To reduce the incidence of perinatal hepatitis B transmission further, the American Academy of Pediatrics endorses the recommendation of the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention that all newborn infants with a birth weight of greater than or equal to 2000 g receive hepatitis B vaccine by 24 hours of age.

DOI10.1542/peds.2017-1870
Alternate JournalPediatrics
PubMed ID28847980