Drugs for the Prevention and Treatment of Sepsis in the Newborn.

TitleDrugs for the Prevention and Treatment of Sepsis in the Newborn.
Publication TypeJournal Article
Year of Publication2019
AuthorsMukhopadhyay S, Wade KC, Puopolo KM
JournalClin Perinatol
Volume46
Issue2
Pagination327-347
Date Published2019 Jun
ISSN1557-9840
Abstract

Antimicrobial medications are the most commonly used medications in the neonatal intensive care unit. Antibiotics are used for infection prophylaxis, empiric treatment, and definitive treatment of confirmed infection. The choice of medication should be informed by the epidemiology and microbiology of infection in specific clinical scenarios and by the clinical condition of the infant. Understanding evolving pathogen susceptibility to antimicrobials and key pharmacotherapy determinants in neonates can inform optimal antibiotic use.

DOI10.1016/j.clp.2019.02.012
Alternate JournalClin Perinatol
PubMed ID31010563
PubMed Central IDPMC6485941
Grant ListK23 HD088753 / HD / NICHD NIH HHS / United States