Disparities in Survival and Health Outcomes in Childhood Leukemia.

TitleDisparities in Survival and Health Outcomes in Childhood Leukemia.
Publication TypeJournal Article
Year of Publication2019
AuthorsWinestone LE, Aplenc R
JournalCurr Hematol Malig Rep
Date Published2019 May 09
ISSN1558-822X
Abstract

PURPOSE OF REVIEW: The aim of this review is to summarize the current literature on pediatric leukemia disparities with attention to not only racial and ethnic disparities, but also socioeconomic disparities. We focus on disparities in survival as well as other health-related outcomes, including end-of-life care and late effects.

RECENT FINDINGS: While progress has been made in decreasing some disparities, most notably in pediatric acute lymphoblastic leukemia, disparities along many axes persist. Proposed etiologies include differences in the genomic alterations of the leukemia itself to differences in access to care that operate through socioeconomic status, insurance, and geographic location. As approaches to therapy become increasingly technical and complex, particular attention to the equitable distribution of these personalized therapeutic interventions is essential. Moving beyond simple descriptive studies to focus on mechanisms of existing disparities will allow for design of interventions to reduce or eliminate disparities in pediatric leukemia.

DOI10.1007/s11899-019-00515-x
Alternate JournalCurr Hematol Malig Rep
PubMed ID31073772