Database Research for Pediatric Infectious Diseases.

TitleDatabase Research for Pediatric Infectious Diseases.
Publication TypeJournal Article
Year of Publication2015
AuthorsKronman MP, Gerber JS, Newland JG, Hersh AL
JournalJ Pediatric Infect Dis Soc
Volume4
Issue2
Pagination143-50
Date Published2015 Jun
ISSN2048-7207
Abstract

Multiple electronic and administrative databases are available for the study of pediatric infectious diseases. In this review, we identify research questions well suited to investigations using these databases and highlight their advantages, including their relatively low cost, efficiency, and ability to detect rare outcomes. We discuss important limitations, including those inherent in observational study designs and the potential for misclassification of exposures and outcomes, and identify strategies for addressing these limitations. We provide examples of commonly used databases and discuss methodologic considerations in undertaking studies using large databases. Last, we propose a checklist for use in planning or evaluating studies of pediatric infectious diseases that employ electronic databases, and we outline additional practical considerations regarding the cost of and how to access commonly used databases.

DOI10.1093/jpids/piv007
Alternate JournalJ Pediatric Infect Dis Soc
PubMed ID26407414