Comparative Effectiveness Research Through a Collaborative Electronic Reporting Consortium.

TitleComparative Effectiveness Research Through a Collaborative Electronic Reporting Consortium.
Publication TypeJournal Article
Year of Publication2015
AuthorsFiks AG, Grundmeier RW, Steffes J, Adams WG, Kaelber DC, Pace WD, Wasserman RC
Corporate AuthorsComparative Effectiveness Research Through Collaborative Electronic Reporting(CER2) Consortium
JournalPediatrics
Volume136
Issue1
Paginatione215-24
Date Published07/2015
ISSN1098-4275
KeywordsChild, Child Welfare, Comparative Effectiveness Research, Cooperative Behavior, Data Collection, Electronic Health Records, Humans, Pediatrics, Research Design, United States
Abstract

The United States lacks a system to use routinely collected electronic health record (EHR) clinical data to conduct comparative effectiveness research (CER) on pediatric drug therapeutics and other child health topics. This Special Article describes the creation and details of a network of EHR networks devised to use clinical data in EHRs for conducting CER, led by the American Academy of Pediatrics Pediatric Research in Office Settings (PROS). To achieve this goal, PROS has linked data from its own EHR-based "ePROS" network with data from independent practices and health systems across the United States. Beginning with 4 of proof-of-concept retrospective CER studies on psychotropic and asthma medication use and side effects with a planned full-scale prospective CER study on treatment of pediatric hypertension, the Comparative Effectiveness Research Through Collaborative Electronic Reporting (CER(2)) collaborators are developing a platform to advance the methodology of pediatric pharmacoepidemiology. CER(2) will provide a resource for future CER studies in pediatric drug therapeutics and other child health topics. This article outlines the vision for and present composition of this network, governance, and challenges and opportunities for using the network to advance child health and health care. The goal of this network is to engage child health researchers from around the United States in participating in collaborative research using the CER(2) database.

DOI10.1542/peds.2015-0673
Alternate JournalPediatrics
PubMed ID26101357
Grant ListR40MC24943 / / PHS HHS / United States
UA6MC15585 / / PHS HHS / United States
UB5MC20286 / / PHS HHS / United States