Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates.

TitleComparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates.
Publication TypeJournal Article
Year of Publication2021
AuthorsMoustafa AM, Bianco C, Denu L, Ahmed A, Coffin SE, Neide B, Everett J, Reddy S, Rabut E, Deseignora J, Feldman MD, Rodino KG, Bushman F, Harris RM, Mell JChang, Planet PJ
JournalOpen Forum Infect Dis
Volume8
Issue7
Paginationofab300
Date Published2021 Jul
ISSN2328-8957
Abstract

We report the genome of a B.1.1.7+E484K severe acute respiratory syndrome coronavirus 2 from Southeastern Pennsylvania and compare it with all high-coverage B.1.1.7+E484K genomes (n = 235) available. Analyses showed the existence of at least 4 distinct clades of this variant circulating in the United States and the possibility of at least 59 independent acquisitions of the E484K mutation.

DOI10.1093/ofid/ofab300
Alternate JournalOpen Forum Infect Dis
PubMed ID34254040
PubMed Central IDPMC8244812