Title | Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Moustafa AM, Bianco C, Denu L, Ahmed A, Coffin SE, Neide B, Everett J, Reddy S, Rabut E, Deseignora J, Feldman MD, Rodino KG, Bushman F, Harris RM, Mell JChang, Planet PJ |
Journal | Open Forum Infect Dis |
Volume | 8 |
Issue | 7 |
Pagination | ofab300 |
Date Published | 2021 Jul |
ISSN | 2328-8957 |
Abstract | We report the genome of a B.1.1.7+E484K severe acute respiratory syndrome coronavirus 2 from Southeastern Pennsylvania and compare it with all high-coverage B.1.1.7+E484K genomes (n = 235) available. Analyses showed the existence of at least 4 distinct clades of this variant circulating in the United States and the possibility of at least 59 independent acquisitions of the E484K mutation. |
DOI | 10.1093/ofid/ofab300 |
Alternate Journal | Open Forum Infect Dis |
PubMed ID | 34254040 |
PubMed Central ID | PMC8244812 |