| Title | CLL/SLL diagnosed in an adolescent. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Luskin M, Wertheim G, Morrissette J, Daber R, Biegel J, Wilmoth DM, Kersun L, King R, Paessler M, Simon C, Aplenc R, Loren A |
| Journal | Pediatr Blood Cancer |
| Volume | 61 |
| Issue | 6 |
| Pagination | 1107-10 |
| Date Published | 2014 Jun |
| ISSN | 1545-5017 |
| Keywords | Adolescent, Age Factors, Ataxia Telangiectasia Mutated Proteins, Biomarkers, Tumor, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 8, Diagnostic Imaging, Gene Dosage, Genes, myc, Humans, Immunophenotyping, In Situ Hybridization, Fluorescence, Leukemia, Lymphocytic, Chronic, B-Cell, Lymph Nodes, Male, Sequence Deletion |
| Abstract | Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a disease of older adults. Pediatric CLL/SLL is vanishingly rare in the literature. We present a case of CLL/SLL diagnosed in a 17-year-old male. The pathologic findings of this case were those of classic CLL/SLL with an ATM deletion, a characteristic genetic abnormality in CLL/SLL. Management guidelines for CLL/SLL are tailored to older adults making determination of the optimal therapy for this patient a unique challenge. |
| DOI | 10.1002/pbc.24884 |
| Alternate Journal | Pediatr Blood Cancer |
| PubMed ID | 24281971 |