Clinical impact of neonatal hypoglycemia screening in the well-baby care.

TitleClinical impact of neonatal hypoglycemia screening in the well-baby care.
Publication TypeJournal Article
Year of Publication2020
AuthorsMukhopadhyay S, Wade KC, Dhudasia MB, Skerritt L, Chou JH, Dukhovny D, Puopolo KM
JournalJ Perinatol
Date Published2020 Mar 09

OBJECTIVES: To determine the proportion of well-appearing newborns screened for hypoglycemia, yield of specific screening criteria, and impact of screening on breastfeeding.

STUDY DESIGN: The retrospective study of well-appearing at-risk infants born ≥36 weeks' gestation with blood glucose (BG) measurements obtained ≤72 h of age.

RESULTS: Of 10,533 eligible well newborns, 48.7% were screened for hypoglycemia. Among tested infants, BG < 50 mg/dL occurred in 43% and 4.6% required intensive care for hypoglycemia. BG < 50 mg/dL was associated with lower rates of exclusive breastfeeding (22% vs 65%, p < 0.001). Infants screened due to late-preterm birth were most frequently identified as hypoglycemic. The fewest abnormal values occurred among appropriate weight, late-term infants of nondiabetic mothers.

CONCLUSION: Hypoglycemia risk criteria result in screening a large proportion of otherwise well newborns and negatively impact rates of exclusive breastfeeding. The risks and benefits of hypoglycemia screening recommendations should be urgently addressed.

Alternate JournalJ Perinatol
PubMed ID32152490
Grant List1K23HD088753-01A1 / / U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) /