Clinical impact of neonatal hypoglycemia screening in the well-baby care.

TitleClinical impact of neonatal hypoglycemia screening in the well-baby care.
Publication TypeJournal Article
Year of Publication2020
AuthorsMukhopadhyay S, Wade KC, Dhudasia MB, Skerritt L, Chou JH, Dukhovny D, Puopolo KM
JournalJ Perinatol
Date Published2020 Mar 09
ISSN1476-5543
Abstract

OBJECTIVES: To determine the proportion of well-appearing newborns screened for hypoglycemia, yield of specific screening criteria, and impact of screening on breastfeeding.

STUDY DESIGN: The retrospective study of well-appearing at-risk infants born ≥36 weeks' gestation with blood glucose (BG) measurements obtained ≤72 h of age.

RESULTS: Of 10,533 eligible well newborns, 48.7% were screened for hypoglycemia. Among tested infants, BG < 50 mg/dL occurred in 43% and 4.6% required intensive care for hypoglycemia. BG < 50 mg/dL was associated with lower rates of exclusive breastfeeding (22% vs 65%, p < 0.001). Infants screened due to late-preterm birth were most frequently identified as hypoglycemic. The fewest abnormal values occurred among appropriate weight, late-term infants of nondiabetic mothers.

CONCLUSION: Hypoglycemia risk criteria result in screening a large proportion of otherwise well newborns and negatively impact rates of exclusive breastfeeding. The risks and benefits of hypoglycemia screening recommendations should be urgently addressed.

DOI10.1038/s41372-020-0641-1
Alternate JournalJ Perinatol
PubMed ID32152490
Grant List1K23HD088753-01A1 / / U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) /