Children's Oncology Group's 2013 blueprint for research: cancer control and supportive care.

TitleChildren's Oncology Group's 2013 blueprint for research: cancer control and supportive care.
Publication TypeJournal Article
Year of Publication2013
AuthorsSung L, Zaoutis TE, Ullrich NJ, Johnston D, Dupuis L, Ladas E
Corporate AuthorsChildren's Oncology Group Cancer Control and Supportive Care Committee
JournalPediatr Blood Cancer
Volume60
Issue6
Pagination1027-30
Date Published2013 Jun
ISSN1545-5017
KeywordsAntineoplastic Agents, Child, Clinical Trials as Topic, Cognition Disorders, Delivery of Health Care, Humans, Infection, Neoplasms, Quality of Life, Radiotherapy, Research
Abstract

In cancer control research, the objective is to reduce overall morbidity and mortality by decreasing acute and delayed treatment-related toxicities in all children with cancer. To date, the Children's Oncology Group (COG) has focused on infection, neurocognition, quality of life (QoL), and nutrition/antiemetics. COG is conducting randomized controlled trials (RCTs) to determine prophylaxis strategies that will reduce infections in high-risk populations. Two RCTs are determining if modafinil or computerized cognitive training improve cognitive functioning in pediatric brain tumor patients. QoL is being assessed in acute leukemia patients. Improved supportive care outcomes will only occur when the most effective interventions are established.

DOI10.1002/pbc.24426
Alternate JournalPediatr Blood Cancer
PubMed ID23255159
PubMed Central IDPMC4447629
Grant ListU10 CA095861 / CA / NCI NIH HHS / United States
U10 CA098543 / CA / NCI NIH HHS / United States
U10 CA95861 / CA / NCI NIH HHS / United States
U10 CA98543 / CA / NCI NIH HHS / United States
U10CA98413 / CA / NCI NIH HHS / United States