Candida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study.

TitleCandida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study.
Publication TypeJournal Article
Year of Publication2014
AuthorsPalazzi DL, Arrieta A, Castagnola E, Halasa N, Hubbard S, Brozovich AA, Fisher BT, Steinbach WJ
JournalPediatr Infect Dis J
Volume33
Issue12
Pagination1294-6
Date Published2014 Dec
ISSN1532-0987
KeywordsAdolescent, Antifungal Agents, Candida, Candidiasis, Invasive, Child, Child, Preschool, Drug Resistance, Fungal, Female, Humans, Infant, Male, Prospective Studies, Treatment Outcome, United States
Abstract

A multi-national prospective study of pediatric patients with invasive candidiasis between August 2007 and September 2012 was performed and included 441 infections. Variation in infecting Candida species and antifungals used was noted between US and non-US sites. Antifungal-associated adverse events were most common with polyene use.

DOI10.1097/INF.0000000000000431
Alternate JournalPediatr. Infect. Dis. J.
PubMed ID24892850