Canadian Acute Respiratory Illness and Flu Scale (CARIFS) for clinical detection of influenza in children.

TitleCanadian Acute Respiratory Illness and Flu Scale (CARIFS) for clinical detection of influenza in children.
Publication TypeJournal Article
Year of Publication2014
AuthorsFischer JB, Prasad PA, Coffin SE, Alpern ER, Mistry RD
JournalClin Pediatr (Phila)
Volume53
Issue12
Pagination1174-80
Date Published2014 Oct
ISSN1938-2707
KeywordsAdolescent, Adult, Child, Child, Preschool, Comorbidity, Diagnosis, Differential, Emergency Service, Hospital, Female, Humans, Infant, Infant, Newborn, Influenza, Human, Male, Orthomyxoviridae, Severity of Illness Index
Abstract

BACKGROUND: Validated clinical scales, such as the Canadian Acute Respiratory Illness and Flu Scale (CARIFS), have not been used to differentiate influenza (FLU) from other respiratory viruses.

METHODS: Secondary analysis of a prospective cohort presenting to the emergency department (ED) with an influenza-like infection from 2008 to 2010. Subjects were children aged 0 to 19 years who had a venipuncture and respiratory virus polymerase chain reaction. Demographics and CARIFS items were assessed during the ED visit; comparisons were made between FLU and non-FLU subjects.

RESULTS: The 203 subjects had median age 30.5 months; 61.6% were male. Comorbid conditions (51.2%) were common. FLU was identified in 26.6%, and were older than non-FLU patients (69.7 vs 47.9 months, P = .02). Demographic, household factors, and mean CARIFS score did not differ between FLU (33.7), and non-FLU (32.0) (mean difference 1.6, 95% CI: -2.0 to 5.2) groups.

CONCLUSIONS: CARIFS cannot discriminate between FLU and non-FLU infection in ED children with influenza-like infection.

DOI10.1177/0009922814542608
Alternate JournalClin Pediatr (Phila)
PubMed ID25009116