Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome.

TitleAssociation of Infection in Neonates and Long-Term Neurodevelopmental Outcome.
Publication TypeJournal Article
Year of Publication2021
AuthorsSewell E, Roberts J, Mukhopadhyay S
JournalClin Perinatol
Volume48
Issue2
Pagination251-261
Date Published2021 Jun
ISSN1557-9840
Abstract

Perinatal and neonatal infection and associated inflammatory response may adversely affect brain development and lead to neurodevelopmental impairment. Factors that predict the risk of infection and subsequent adverse outcomes have been identified but substantial gaps remain in identifying mechanisms and interventions that can alter outcomes. This article describes the current epidemiology of neonatal sepsis, the pathogenesis of brain injury with sepsis, and the reported long-term neurodevelopment outcomes among survivors.

DOI10.1016/j.clp.2021.03.001
Alternate JournalClin Perinatol
PubMed ID34030812