Association Between Vancomycin Trough Concentrations and Duration of Methicillin-Resistant Staphylococcus aureus Bacteremia in Children.

TitleAssociation Between Vancomycin Trough Concentrations and Duration of Methicillin-Resistant Staphylococcus aureus Bacteremia in Children.
Publication TypeJournal Article
Year of Publication2018
AuthorsHsu AJ, Hamdy RF, Huang Y, Olson JA, Ghobrial S, Gerber JS, Hersh AL, Tamma PD
JournalJ Pediatric Infect Dis Soc
Volume7
Start Page338
Issue4
Pagination338-341
Date Published2018 Dec 3
ISSN2048-7207
Abstract

In a multicenter retrospective study, we sought to determine the optimal vancomycin trough concentration that would impact the duration of methicillin-resistant Staphylococcus aureus bacteremia in children. We found that a median vancomycin trough concentration of <10 µg/mL within the first 72 hours may be associated with a longer duration of bacteremia compared to a median trough concentration of ≥10 µg/mL.

DOI10.1093/jpids/pix068
Alternate JournalJ Pediatric Infect Dis Soc
PubMed ID28992126