Sabrina Gmuca, MD, MSCE

Core Faculty

Sabrina Gmuca, MD, MSCE is a core faculty member at the Center for Pediatric Clinical Effectiveness (CPCE) at the Children's Hospital of Philadelphia (CHOP), an attending physician in the Division of Rheumatology, and an instructor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

Dr. Gmuca seeks to enhance the care of children with a variety of rheumatic diseases. Her current research addresses amplified musculoskeletal pain syndrome (AMPS), including juvenile fibromyalgia syndrome (JFMS), which is a major public health issue because of its high prevalence, related socioeconomic burden, and associated risk of opioid exposure. She is using large datasets to identify prevailing treatment regimens for JFMS as well as risk factors associated with opioid exposure. This will hopefully lead to targeted intervention strategies to prevent the overuse and misuse of opioid medications, and standardized treatment guidelines to reduce variation across practices.

Dr. Gmuca is also interested in the cross-section of neurology and rheumatology. She previously received a CPCE Pilot Grant to investigate “Treatment and outcomes in Neuromyelitis Optica (NMO).” The main aim of this study is to compare the likelihood of re-hospitalization in pediatric patients with NMO treated with rituximab versus those children treated with alternative therapies.

Contact Dr. Gmuca at

To view Dr. Gmuca's peer-reviewed publications, click here.